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presentation

Differential Gene Expression Analysis of RNA-sequencing Data: Evaluation of DGE tools for long non-coding RNA-sequencing data

Alemu Takele Assefa, Jo Vandesompele, Olivier Thas Published in 2018

PhD

Deciphering the untranslated message in T-cell acute lymphoblastic leukemia

Annelynn Wallaert Public defense: 2017-04-28 17:00

T-cell acute lymphoblastic leukemia (T-ALL) patients currently present with an overall favorable ...

presentation

Nonparametric Simulation to Evaluate the Performance of Statistical Methods for Differential Gene Expression Analysis of long...

Alemu Takele Assefa, Olivier Thas, Jo Vandesompele Published in 2017 in Hsselt

The discovery and study of lncRNAs is of major relevance to human biology and disease since they ...

article

Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data

Alemu Takele Assefa, Katrijn De Paepe, Celine Everaert, Pieter Mestdagh, Olivier Thas and 1 more (2018) GENOME BIOLOGY

Background: Long non-coding RNAs (lncRNAs) are typically expressed at low levels and are inherent...

article

Noncoding after all : biases in proteomics data do not explain observed absence of lncRNA translation products

Kenneth Verheggen, Pieter-Jan Volders, Pieter Mestdagh, Gerben Menschaert, Petra Van Damme and 3 more (2017) JOURNAL OF PROTEOME RESEARCH

Over the past decade, long noncoding RNAs (lncRNAs) have emerged as novel functional entities of ...

article

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

Farzaneh Ghazavi, Barbara De Moerloose, Wouter Van Loocke, Annelynn Wallaert, Hetty Helsmoortel and 12 more (2016) ONCOTARGET

Overwhelming evidence indicates that long non-coding RNAs have essential roles in tumorigenesis. ...

presentation

RNA-directed proteomics to explore the interactome of the melanoma-specific lncRNA SAMMSON

Louis Delhaye, Shanna Dewaele, Delphine De Sutter, Pieter Mestdagh, Sven Eyckerman

The last decade, there has been an increasing support for the involvement of long non-coding RNAs...

article

Differential expression of lncRNAs during the HIV replication cycle : an underestimated layer in the HIV-host interplay

Wim Trypsteen, Pejman Mohammadi, Clarissa Van Hecke, Pieter Mestdagh, Steve Lefever and 6 more (2016) SCIENTIFIC REPORTS

Studying the effects of HIV infection on the host transcriptome has typically focused on protein-...

book

Emerging roles of long noncoding RNAs in neurological diseases and metabolic disorders

William Cho, Romano Regazzi, Yingqun Huang Frontiers Media SA 2015

Long noncoding RNAs (lncRNAs) are a new class of transcripts that are in general longer than 200 ...

article

Long non-coding RNAs in cutaneous melanoma : clinical perspectives

Eva Hulstaert, Lieve Brochez, Pieter-Jan Volders, Jo Vandesompele, Pieter Mestdagh (2017) ONCOTARGET

Metastatic melanoma of the skin has a high mortality despite the recent introduction of targeted ...

article

Long non-coding RNAs in leukemia : biology and clinical impact

Tim Lammens, Kaat Durinck, Annelynn Wallaert, Franki Speleman, Pieter Van Vlierberghe (2017) CURRENT OPINION IN HEMATOLOGY

Purpose of review: Over the last years, long non-coding RNAs (lncRNAs) have emerged as putative r...

article

T-ALL and thymocytes : a message of noncoding RNAs

Annelynn Wallaert, Kaat Durinck, Tom Taghon, Pieter Van Vlierberghe, Franki Speleman (2017) JOURNAL OF HEMATOLOGY & ONCOLOGY

In the last decade, the role for noncoding RNAs in disease was clearly established, starting with...

book

Regulation by non-coding RNAs

MDPI AG - Multidisciplinary Digital Publishing Institute 2014

Regulatory non-protein-coding RNA genes and their transcripts were first found and characterized ...

book

Regulation by non-coding RNAs

MDPI AG - Multidisciplinary Digital Publishing Institute 2014

Regulatory non-protein-coding RNA genes and their transcripts were first found and characterized ...

article

Influence of microRNAs and long non-coding RNAs in cancer chemoresistance

Duncan Ayers, Jo Vandesompele (2017) GENES

Innate and acquired chemoresistance exhibited by most tumours exposed to conventional chemotherap...

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