TY - JOUR UR - http://lib.ugent.be/catalog/pug01:138731 ID - pug01:138731 LA - eng TI - A plant-specific cyclin-dependent kinase is involved in the control of G₂/M progression in plants PY - 2001 JO - (2001) JOURNAL OF BIOLOGICAL CHEMISTRY SN - 0021-9258 PB - 2001 AU - Porceddu, Andrea AU - Stals, Hilde AU - Reichheld, Jean-Philippe AU - Segers, Gerda AU - De Veylder, Lieven AU - Barrôco, Rosa de Pinho AU - Casteels, Peter AU - Van Montagu, Marc AU - Inzé, Dirk WE09 801000556997 0000-0002-3217-8407 AU - Mironov, Vladimir AB - Cyclin-dependent kinases (CDKs) control the key transitions in the eukaryotic cell cycle. All the CDKs known to control G(2)/M progression in yeast and animals are distinguished by the characteristic PSTAIRE motif in their cyclin-binding domain and are closely related. Higher plants contain in addition a number of more divergent non-PSTAIRE CDKs with still obscure functions. We show that a plant-specific type of non-PSTAIRE CDKs is involved in the control of the G(2)/M progression. In synchronized tobacco BY-2 cells, the corresponding protein, accumulated in a cell cycle-regulated fashion, peaking at the G(2)/M transition. The associated histone HI kinase activity reached a maximum in mitosis and required a yet unidentified subunit to be fully active. Down-regulation of the associated kinase activity in transgenic tobacco plants using a dominant-negative mutation delayed G(2)/M transition. These results provide the first evidence that non-PSTAIRE CDKs are involved in the control of the G(2)/M progression in plants. ER -Download RIS file
| 00000nam^a2200301^i^4500 | |||
| 001 | 138731 | ||
| 005 | 20180813140904.0 | ||
| 008 | 040114s2001------------------------eng-- | ||
| 022 | a 0021-9258 | ||
| 024 | a 000171194500041 2 wos | ||
| 024 | a 1854/LU-138731 2 handle | ||
| 024 | a 10.1074/jbc.M011060200 2 doi | ||
| 040 | a UGent | ||
| 245 | a A plant-specific cyclin-dependent kinase is involved in the control of G₂/M progression in plants | ||
| 246 | a A plant-specific cyclin-dependent kinase is involved in the control of G(2)/M progression in plants | ||
| 260 | c 2001 | ||
| 520 | a Cyclin-dependent kinases (CDKs) control the key transitions in the eukaryotic cell cycle. All the CDKs known to control G(2)/M progression in yeast and animals are distinguished by the characteristic PSTAIRE motif in their cyclin-binding domain and are closely related. Higher plants contain in addition a number of more divergent non-PSTAIRE CDKs with still obscure functions. We show that a plant-specific type of non-PSTAIRE CDKs is involved in the control of the G(2)/M progression. In synchronized tobacco BY-2 cells, the corresponding protein, accumulated in a cell cycle-regulated fashion, peaking at the G(2)/M transition. The associated histone HI kinase activity reached a maximum in mitosis and required a yet unidentified subunit to be fully active. Down-regulation of the associated kinase activity in transgenic tobacco plants using a dominant-negative mutation delayed G(2)/M transition. These results provide the first evidence that non-PSTAIRE CDKs are involved in the control of the G(2)/M progression in plants. | ||
| 598 | a A1 | ||
| 100 | a Porceddu, Andrea | ||
| 700 | a Stals, Hilde u WE09 0 801000970259 9 72C866CE-B25E-11E6-B104-2D2FD0AF0289 | ||
| 700 | a Reichheld, Jean-Philippe u WE09 0 801001086154 9 7340CE20-B25E-11E6-B104-2D2FD0AF0289 | ||
| 700 | a Segers, Gerda u WE09 0 801000849516 9 7704C002-B25E-11E6-B104-2D2FD0AF0289 | ||
| 700 | a De Veylder, Lieven u WE09 0 801000929338 9 F4C04C64-F0ED-11E1-A9DE-61C894A0A6B4 | ||
| 700 | a Barrôco, Rosa de Pinho | ||
| 700 | a Casteels, Peter u WE09 0 801001002288 9 72ABE2BA-B25E-11E6-B104-2D2FD0AF0289 | ||
| 700 | a Van Montagu, Marc u WE09 0 801000030672 9 FB1E4F3E-F0ED-11E1-A9DE-61C894A0A6B4 | ||
| 700 | a Inzé, Dirk u WE09 0 801000556997 0 0000-0002-3217-8407 9 F421514A-F0ED-11E1-A9DE-61C894A0A6B4 | ||
| 700 | a Mironov, Vladimir u WE09 0 801001222661 9 6D7EB934-B25E-11E6-B104-2D2FD0AF0289 | ||
| 650 | a Biology and Life Sciences | ||
| 653 | a ORYZA-SATIVA | ||
| 653 | a S-PHASE | ||
| 653 | a CDC2 GENE | ||
| 653 | a ALFALFA CELLS | ||
| 653 | a TRANSGENIC TOBACCO | ||
| 653 | a FUNCTIONAL HOMOLOG | ||
| 653 | a FISSION YEAST | ||
| 653 | a PROTEIN-KINASE | ||
| 653 | a CELL-CYCLE | ||
| 653 | a ARABIDOPSIS-THALIANA | ||
| 773 | t JOURNAL OF BIOLOGICAL CHEMISTRY g J. Biol. Chem. 2001. 276 (39) p.36354-36360 q 276:39<36354 | ||
| 856 | 3 Full Text u https://biblio.ugent.be/publication/138731/file/4148237 z [ugent] y 138731_Porceddu_et_al.__2001_JBiolChem276_36354.pdf | ||
| 920 | a article | ||
| Z30 | x VI 1 VIB | ||
| 922 | a UGENT-EA | ||
| Z30 | x WE 1 WE09 | ||
| 922 | a UGENT-WE | ||
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